If you're used to playing coated strings, you're going to have a rough (literally) time with these.
I've used nickel strings mainly before purchasing these for my Ibanez BTB, and it feels like I've made a switch from 360p to 1080p HD.
HOWEVER, it seems that the super crystal clear sound doesn't last too long. These will sound super bright for a week and a half or so, and degrade down to almost nickelwound like sound.