Well, the cable itself doesn't have a sound of course but it doesn't seem to affect the sound of my guitar. I use relatively short cables from the guitar to the first device with a buffer but even so this cable seems great, no detectable colouration or loss.
Previously I was using a Van Damme cable of around the same length which also is very transparent but one minor con with the Spirit cable is that it is a lot more prone to kinking up compared to the Vad Damme cable - that might just be because it is a lot newer and a bit stiffer though. The cable feels pretty substantial, was nice to work with and fits well into the Neutrik connectors I fitted. The cable construction is very nice, great quality with both copper woven screen and conductive plastic layer, no nise or interference at all.