I have settled on Elixir after trying most big string brands.
My hands get quite sweaty, this is the only brand that has the strings last for a reasonable time before corroding.
The sound is also really really good, the optiweb is not a lot better than nanoweb, but the difference is enough for me to look for these every time.
Now for the gauge, the 10-52 is great if you want that punchy rhythm chug on the power chords but do not want to do a lot of effort to bend. It works well for E standard, D standard or drop C tunings alike. Too bad the local shops don't stock enough of them and elixir is not selling packs of 10.