I play these in E, Eb, D, and drop C and they hold the tension really well on a 24,75 inch scale, and on a bigger scale you could go all the way down to drop B. These strings are not coated so they won't last more than two months (or even less, depends on how much your hands sweat, how hard you play and how often). If you want to do drop tunings or just want a more well-balanced set, go with this one. The extra tension avoids the notes to go sharp if you play hard and makes it easier to deal with fret buzz. If you're going to use this set for a 7 string, I suggest you a 64 for the bottom string.