I have two sets of monitor speakers, plus a headphone amp for recording.
In Presonus Studio One 6 you need, for recording, to use output 3 and 4 for the special "cue" mix, to minimise latency. The Station is perfect for the needed switching. If you want your "cue" mix on the main speakers (in case of instruments needing no microphone), you just switch the main input to "ST2" and you get the "cue" mix. I can recommend using two different speakers (Speakers A and B): one very good, strong pair of speakers (like my Adam Audio) for super sound - and one "every day" speaker pair like my Presonus Eris 4.5. They are less tiring to listen to. For "Speakers C" I could imagine Auratones or similar, to check the mix.
In addition, the Station V2 has headphone sockets that I can switch between "main" and "cue". The headphone sound is very powerful and cristal clear.
Update after longer use: The volume poti is noisy (especially at very low volume), it is not extreme, but really disturbing in use. I have seen that I am not the only one having this issue - so it seems that Presonus has to act here! I go down to 4 stars overall and 3 stars for quality..... today I removed the noise by spraying a bit of "Electro Contact Reiniger" at the poti axle (after removing the knob, leaving the poti installed). Update after several months: the issue is coming back. So not very happy.