I thought I was being very clever when I ordered this for my Squire Affinity Stratocaster. The stock Squier tuners use a two-dimple mounting system and so do the Fender locking tuners. Simple upgrade, right?
No!
The two dimples on the Fender locking tuners do *not* match the pre-drilled holes in the headstock. It is definitely possible to drill new holes for the dimples though and if you look online there are some videos, which show the process. It requires 12 new holes to be drilled and care taken to make sure that all of the tuners wil line up straight when installed. I managed to complete the installation cleanly but I'll readily admit that this carries risk and many people will be justifiably unwilling to perform the modifications to their guitar.
So... It's definitely possible on a Squier Affinity but there are easier alternatives, which carry less risk.
The tuners themselves are very nice, with a smooth and secure action. String changes are very easy and tuning stability has been decent. It was a pain to modify my guitar to fit these tuners but the end result has been worthwhile.